South Sacramento benefits from its strategic location near major transportation routes. It is situated along Interstate 5, one of the primary north-south highways on the West Coast, providing convenient access to regional and international markets. The area is also served by the Union Pacific Railroad and is in close proximity to the Sacramento International Airport, facilitating efficient movement of goods. South Sacramento hosts several industry clusters that play a significant role in its industrial sector. These clusters include manufacturing, logistics and distribution, food processing, agriculture, and construction. The region has a strong manufacturing base, with companies involved in sectors such as automotive, electronics, metal fabrication, and plastics

The industrial business sector in South Sacramento generates a substantial number of jobs for the local workforce. The presence of diverse industries provides employment opportunities across various skill levels. Manufacturing and logistics companies, in particular, contribute significantly to job creation in the region. South Sacramento offers a favorable business environment for industrial enterprises. The area has a supportive local government that encourages economic development and works to attract and retain industrial businesses. There are industrial parks and commercial spaces available for lease or purchase, accommodating the needs of different industries